No, at least not because of gearing.
Here is an example using simple gear ratios and an 8000rpm change point.
Formula: (8000/lower ratio)*higher ratio
Code:
Gear Ratio Final Drive RPM After Change Final Drive 2 RPM after change 2
4.2 4.1
4.0 16.8 16.4
3.0 12.6 6000.0 12.3 6000.0
2.0 8.4 5333.3 8.2 5333.3
1.0 4.2 4000.0 4.1 4000.0
As you can see, lengthening the final drive (by fitting larger dia tyres) does nothing for the RPM drop due to gearing.
It certainly could affect it in other ways however.
Edit: Hardly a neat table, but it is all there.
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